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Tebuconazole — toxicity, side effects, diseases and environmental impacts
Aug 16, 2018

Tebuconazole is a triazole fungicide used to keep field crops and cereals free of pathogenic fungicide. This chemical works by inhibiting ergosterol biosynthesis, which is the metabolic pathway necessary for generating a major fungal plasma membrane constituent. Tebucanozole can be used as a seed dressing to remedy cereal bunt and smut disease, or as a foliar spray to control mildew and scale in a variety of crops.

Despite its wide usage, tebuconazole is considered to be a potentially dangerous substance. The World Health Organization (WHO) has deemed tebuconazole to be a “slightly hazardous” substance and an “acute hazard”, while the United States Environmental Protection Agency (EPA) has noted down tebuconazole as a “moderately toxic” chemical.

Tebuconazole is a suspected reproductive toxin. To be more precise, tebuconazole is suspected of being capable of damaging fertility or children while they’re still in the womb. A multitude of studies presented in 2006 by the California Environmental Protection Agency/Department of Pesticide Regulation have noted that fetuses of lab rats that had been dosed with tebuconazole had reduced body weights, instances of missing tails, malformed faces, and even decreased litter sizes.

As per the EPA, tebuconazole is a possible human carcinogen. Several studies that focused on the potential carcinogenicity of tebuconazole have found that it can increase the incidence of thyroid tumors in male rats, and liver tumors in both mice sexes.

Avoid ocular contact with tebuconazole. This chemical is known to be a mild eye irritant.

Swallowing tebuconazole can be dangerous as this chemical can lead to acute oral toxicity.

Heating tebuconazole will lead to its decomposition, which can then cause this substance to emit vapors containing nitrogen oxides and hydrogen chloride.

Tebuconazole should never be used in close proximity to bodies of water. Doing so can result in detrimental environmental effects, since tebuconazole is moderately toxic to fish and highly toxic to zooplankton. Moreover, this chemical can bring about mollusk intoxication.